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熔點 | 315.5-317.5°C |
溶解性 | Soluble in DMSO (55 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), 1% DMSO/30% polyethylene glycol/1% Tween 80 (15 mg/ml at 25 °C), and THF (sparingly). |
存貯條件 | 儲存溫度2-8℃ |
應(yīng)用 | Pomalidomide is a second generation immunomodulator, TNF-α inhibitor, and thalidomide analog. An inhibitor of LPS-induced TNFαrelease. |
產(chǎn)品介紹 | Pomalidomide抑制LPS誘導(dǎo)的TNF-alpha釋放, IC50為13 nM。 |
備注 | Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM. |
生化機(jī)理 | Pomalidomide is tumor necrosis factor-α inhibitor and a new immunomodulator with an IC50 of 1 μM.Pomalidomide is thalidomide derivative that displays inhibition of LPS-induced TNFα release. Shows immunomodulator and anticancer effects. |
別名 | CC-4047;3-氨基-N-(2,6-二氧代-3-哌啶基)鄰苯二甲酰亞胺;泊馬度胺;TNF-alpha抑制劑;IMiD 3;1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline;3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide;4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
Pomalidomide由上海阿拉丁生化科技股份有限公司 為您提供,如您想了解更多關(guān)于Pomalidomide 報價、貨號、參數(shù)等信息,歡迎來電或留言咨詢。
注:該產(chǎn)品未在中華人民共和國食品藥品監(jiān)督管理部門申請醫(yī)療器械注冊和備案,不可用于臨床診斷或治療等相關(guān)用途。